MicroRNAs and Presbycusis
نویسندگان
چکیده
منابع مشابه
MicroRNAs and Presbycusis
Presbycusis (age-related hearing loss) is the most universal sensory degenerative disease in elderly people caused by the degeneration of cochlear cells. Non-coding microRNAs (miRNAs) play a fundamental role in gene regulation in almost every multicellular organism, and control the aging processes. It has been identified that various miRNAs are up- or down-regulated during mammalian aging proce...
متن کاملGenetics of presbycusis and presbystasis.
Presbycusis and presbystasis represent relevant problems of aging, caused by the increase in life expectancy in developed countries. As such, it is advantageous to better understand the physiopathological mechanisms of these age-related inner ear diseases. The hypothesis that presbycusis and presbystasis have a genetic background was proposed some years ago. Several studies (in humans and anima...
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Age-related hearing loss (ARHL) or presbycusis is a complex phenomenon consisting of elevation of the hearing levels as well as changes in the auditory processing. Although many adults retain good hearing as they age, hearing loss associated with ageing is common among elderly persons. There are a number of pathophysiological processes underlying age-related changes to functional components. Pr...
متن کاملComprehensive management of presbycusis: central and peripheral.
The prevailing otolaryngologic approach to treatment of age-related hearing loss (ARHL), presbycusis, emphasizes compensation of peripheral functional deficits (ie, hearing aids and cochlear implants). This approach does not address adequately the needs of the geriatric population, 1 in 5 of whom is expected to consist of the "old old" in the coming decades. Aging affects both the peripheral an...
متن کاملManagement of tinnitus in patients with presbycusis.
Sensorineural hearing loss in elderly patients (presbycusis) relatively often coexists with annoying tinnitus (termed presbytinnitus [PT] by Claussen). The purpose of this study was to verify the conditions of improvement in patients treated for PT. We fitted with hearing aids 33 PT patients (ages 60-89 years) and questioned them about subjective hearing results. Assessment tools included compr...
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ژورنال
عنوان ژورنال: Aging and Disease
سال: 2018
ISSN: 2152-5250
DOI: 10.14336/ad.2017.0119